BCL3 anticorps (C-Term)

N° du produit ABIN6991805

L’anticorps Lapin Polyclonal anti-BCL3 a été validé pour WB et ELISA. Il convient pour détecter BCL3 dans des échantillons de Humain.

Aperçu rapide pour BCL3 anticorps (C-Term) (ABIN6991805)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BCL3 anticorps

Épitope: AA 360-410, C-Term

Purification: BCL3 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3. The immunogen is located within amino acids 360 - 410 of BCL3.

Isotype: IgG

Information d'application

Indications d'application: BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BCL3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3

Sujet: BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ,-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ,-B proteins. The expression of this gene can be induced by NF-κ,-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ,-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.

Poids moléculaire: Predicted: 50 kDa

ID gène: 602

NCBI Accession: NP_005169

UniProt: P20749

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus