CD59 anticorps (N-Term)

N° du produit ABIN6991822

Cet anticorps Lapin Polyclonal détecte spécifiquement CD59 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CD59 anticorps (N-Term) (ABIN6991822)

Antigène: CD59

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD59 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD59 anticorps

Épitope: N-Term

Purification: CD59 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59. The immunogen is located within the first 50 amino acids of CD59.

Isotype: IgG

Information d'application

Indications d'application: CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CD59 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CD59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CD59

Antigène: CD59

Autre désignation: CD59

Sujet: CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.

Poids moléculaire: 14 kDa

ID gène: 966

NCBI Accession: NP_000602

UniProt: P13987

Pathways: Système du Complément