DDX41 anticorps (N-Term)

N° du produit ABIN6991862

L’anticorps Lapin Polyclonal anti-DDX41 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter DDX41 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DDX41 anticorps (N-Term) (ABIN6991862)

Antigène: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX41 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DDX41 anticorps

Épitope: AA 230-280, N-Term

Specificité: At least two isoforms of DDX41 are known to exist, this antibody will detect both isoforms.

Purification: DDX41 Antibody is affinity chromatography purified via peptide column.

Immunogène: DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41. The immunogen is located within amino acids 230 - 280 of DDX41.

Isotype: IgG

Information d'application

Indications d'application: DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DDX41 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DDX41 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur DDX41

Antigène: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Autre désignation: DDX41

Sujet: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.

Poids moléculaire: Predicted: 68 kDa

Observed: 70 kDa

ID gène: 51428

NCBI Accession: NP_057306

UniProt: Q9UJV9