HDAC1 anticorps (C-Term)

N° du produit ABIN6992034

Cet anticorps anti-HDAC1 est un anticorps Lapin Polyclonal détectant HDAC1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour HDAC1 anticorps (C-Term) (ABIN6992034)

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HDAC1 anticorps

Épitope: C-Term

Specificité: HDAC1 antibody is human, mouse and rat reactive. HDAC1 antibody is predicted to not cross-react with other members of the HDAC family.

Purification: HDAC1 antibody is affinity chromatography purified via peptide column.

Immunogène: HDAC1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HDAC1. The immunogen is located within the last 50 amino acids of HDAC1.

Isotype: IgG

Information d'application

Indications d'application: HDAC1 antibody can be used for detection of HDAC1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: HDAC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: HDAC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur HDAC1

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Autre désignation: HDAC1

Sujet: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (1,2). HDAC1 gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (3,4).

Poids moléculaire: Predicted: 53 kDa

Observed: 54 kDa

ID gène: 3065

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis