HDAC2 anticorps (C-Term)

N° du produit ABIN6992035

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC2 dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HDAC2 anticorps (C-Term) (ABIN6992035)

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HDAC2 anticorps

Épitope: C-Term

Specificité: HDAC2 antibody is human, mouse and rat reactive. At least two isoforms of HDAC2 are known to exist, this antibody will detect both isoforms. HDAC2 antibody is predicted to not cross-react with other members of the HDAC family.

Purification: HDAC2 antibody is affinity chromatography purified via peptide column.

Immunogène: HDAC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human HDAC2. The immunogen is located within the last 50 amino acids of HDAC2.

Isotype: IgG

Information d'application

Indications d'application: HDAC2 antibody can be used for detection of HDAC2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: HDAC2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: HDAC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur HDAC2

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Autre désignation: HDAC2

Sujet: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC2 was first identified as as a mammalian homolog to the yeast transcriptional regulator RPD3 (2). HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor (2,3). Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events (4).

Poids moléculaire: Predicted: 54 kDa

Observed: 52 kDa

ID gène: 3066

NCBI Accession: NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2