GLIS2 anticorps (AA 260-310)
Aperçu rapide pour GLIS2 anticorps (AA 260-310) (ABIN6992104)
Antigène
Voir toutes GLIS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 260-310
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Specificité
- GLIS2 antibody is human, mouse and rat reactive.
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Purification
- GLIS2 antibody is affinity chromatography purified via peptide column.
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Immunogène
- GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2. The immunogen is located within amino acids 260 - 310 of GLIS2.
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Isotype
- IgG
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Indications d'application
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GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- GLIS2 antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- GLIS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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Autre désignation
- GLIS2
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Sujet
- GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).
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Poids moléculaire
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Predicted: 58 kDa
Observed: 60 kDa -
ID gène
- 84662
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NCBI Accession
- NP_115964
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UniProt
- Q9BZE0
Antigène
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