PMEPA1 anticorps (AA 160-210)

N° du produit ABIN6992158

Cet anticorps Lapin Polyclonal détecte spécifiquement PMEPA1 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PMEPA1 anticorps (AA 160-210) (ABIN6992158)

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PMEPA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PMEPA1 anticorps

Épitope: AA 160-210

Specificité: PMEPA1 antibody is human, mouse and rat reactive. At least four isoforms are known to exist, this antibody will detect all of the isoforms.

Purification: PMEPA1 antibody is affinity chromatography purified via peptide column.

Immunogène: PMEPA1 antibody was raised against a 16 amino acid peptide near the center of human PMEPA1. The immunogen is located within amino acids 160 - 210 of PMEPA1.

Isotype: IgG

Information d'application

Indications d'application: PMEPA1 antibody can be used for detection of PMEPA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PMEPA1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PMEPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PMEPA1

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Autre désignation: PMEPA1

Sujet: The prostate transmembrane protein, androgen induced 1 (PMEPA1) protein is a transmembrane protein that contains a Smad interacting motif (SIM) (1,2). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins (3). Overexpression of this gene may play a role in multiple types of cancer (2,4).

Poids moléculaire: Predicted: 26, 28, 32 kDa

Observed: 27 kDa

ID gène: 56937

NCBI Accession: NP_064567

UniProt: Q969W9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway