RNF121 anticorps (C-Term)

N° du produit ABIN6992161

Détail du produit anti-RNF121 anticorps

Antigène: RNF121 (Ring Finger Protein 121 (RNF121))

Épitope: AA 260-310, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF121 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificité: RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

Purification: RNF121 antibody is affinity chromatography purified via peptide column.

Immunogène: RNF121 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RNF121. The immunogen is located within amino acids 260 - 310 of RNF121.

Isotype: IgG

Information d'application

Indications d'application: RNF121 antibody can be used for detection of RNF121 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RNF121 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RNF121 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur RNF121

Antigène: RNF121 (Ring Finger Protein 121 (RNF121))

Autre désignation: RNF121 (RNF121 Produits)

Synonymes: anticorps 4930544L10Rik, anticorps im:6907121, anticorps si:ch73-373k7.1, anticorps ring finger protein 121, anticorps RING finger protein 121, anticorps RNF121, anticorps rnf-121, anticorps Rnf121, anticorps rnf121

Sujet: RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).

Poids moléculaire: Predicted: 24, 27, 36 kDa

Observed: 28 kDa

ID gène: 552978

NCBI Accession: NP_060790

UniProt: Q9H920

Pathways: ER-Nucleus Signaling