PDGFA anticorps

N° du produit ABIN7238300

Détail du produit anti-PDGFA anticorps

Antigène: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFA est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human PDGFA

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDGFA

Antigène: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Autre désignation: PDGFA (PDGFA Produits)

Synonymes: anticorps PDGF-A, anticorps PDGF1, anticorps pdgfa, anticorps pdgfa-2, anticorps zgc:100777, anticorps pdgf, anticorps pdgf1, anticorps pdgf-a, anticorps AA409063, anticorps CD142, anticorps Cf-3, anticorps Cf3, anticorps TF, anticorps PDGFACP, anticorps wu:fc32c12, anticorps zgc:153249, anticorps platelet derived growth factor subunit A, anticorps platelet-derived growth factor alpha polypeptide a, anticorps coagulation factor III, anticorps platelet derived growth factor, alpha, anticorps platelet derived growth factor subunit A S homeolog, anticorps platelet-derived growth factor alpha polypeptide b, anticorps PDGFA, anticorps pdgfaa, anticorps pdgfa, anticorps F3, anticorps Pdgfa, anticorps pdgfa.S, anticorps pdgfab

Sujet: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.

NCBI Accession: NP_002598

UniProt: P04085

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling