NLRP10 anticorps

N° du produit ABIN7001412

Détail du produit anti-NLRP10 anticorps

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human NLRP10

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NLRP10 (NLRP10 Produits)

Synonymes: anticorps CLR11.1, anticorps NALP10, anticorps NOD8, anticorps PAN5, anticorps PYNOD, anticorps 6430548I20Rik, anticorps Nalp10, anticorps Napl10, anticorps Pynod, anticorps NLR family pyrin domain containing 10, anticorps NLR family, pyrin domain containing 10, anticorps NLRP10, anticorps Nlrp10

Sujet: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

Poids moléculaire: 75 kDa

NCBI Accession: NP_789791

UniProt: Q86W26

Pathways: Inflammasome