ROR1 anticorps

N° du produit ABIN7239476

L’anticorps Lapin Polyclonal anti-ROR1 a été validé pour ELISA et IHC. Il convient pour détecter ROR1 dans des échantillons de Humain et Souris.

Aperçu rapide pour ROR1 anticorps (ABIN7239476)

Antigène: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ROR1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human ROR1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ROR1

Antigène: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Autre désignation: ROR1

Sujet: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI Accession: NP_005003

UniProt: Q01973

Pathways: Signalisation RTK, Signalisation WNT, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha