Hexokinase 2 anticorps
Aperçu rapide pour Hexokinase 2 anticorps (ABIN7240724)
Antigène
Voir toutes Hexokinase 2 (HK2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human HK2
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:5000, IHC 1:100-1:300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Hexokinase 2 (HK2)
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Autre désignation
- HK2
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Sujet
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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Poids moléculaire
- 102 kDa
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UniProt
- P52789
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Pathways
- Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg
Antigène
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