IL15RA anticorps

N° du produit ABIN7242230

L’anticorps anti-IL15RA Polyclonal Lapin est utilisé pour la détection de IL15RA dans des échantillons de Humain et Souris. Il a été validé pour ELISA et IHC.

Aperçu rapide pour IL15RA anticorps (ABIN7242230)

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL15RA est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IL15RA anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human IL15RA

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IL15RA

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Autre désignation: IL15RA

Sujet: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

NCBI Accession: NP_001230468

UniProt: Q13261

Pathways: Signalistation JAK/STAT