SOCS1 anticorps

N° du produit ABIN7242437

Détail du produit anti-SOCS1 anticorps

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SOCS1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SOCS1

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Autre désignation: SOCS1 (SOCS1 Produits)

Synonymes: anticorps socs1, anticorps zgc:91868, anticorps jab, anticorps cis1, anticorps ssi1, anticorps tip3, anticorps cish1, anticorps ssi-1, anticorps socs-1, anticorps SOCS1, anticorps LOC100228306, anticorps socs1b, anticorps CIS1, anticorps CISH1, anticorps JAB, anticorps SOCS-1, anticorps SSI-1, anticorps SSI1, anticorps TIP3, anticorps Cish1, anticorps Cish7, anticorps Socs-1, anticorps suppressor of cytokine signaling 1a, anticorps suppressor of cytokine signaling 1, anticorps suppressor of cytokine signaling 1 L homeolog, anticorps socs1a, anticorps socs1, anticorps SOCS1, anticorps socs1.L, anticorps Socs1

Sujet: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Poids moléculaire: 24 kDa

NCBI Accession: NP_003736

UniProt: O15524

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Signalisation TLR, Response to Growth Hormone Stimulus