DCC anticorps

N° du produit ABIN7242482

Cet anticorps anti-DCC est un anticorps Lapin Polyclonal détectant DCC dans ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour DCC anticorps (ABIN7242482)

Antigène: DCC (Deleted in Colorectal Carcinoma (DCC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCC est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DCC anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human DCC

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DCC

Antigène: DCC (Deleted in Colorectal Carcinoma (DCC))

Autre désignation: DCC

Sujet: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

NCBI Accession: NP_005206

UniProt: P43146

Pathways: Regulation of Cell Size