Lamin B1 anticorps
Aperçu rapide pour Lamin B1 anticorps (ABIN7245590)
Antigène
Voir toutes Lamin B1 (LMNB1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Fusion protein of human LMNB1
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Lamin B1 (LMNB1)
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Autre désignation
- LMNB1
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Sujet
- The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
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Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 67 kDa
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UniProt
- P20700
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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