ISCU anticorps

N° du produit ABIN7246487

L’anticorps anti-ISCU Polyclonal produit chez le Lapin a été validé pour WB et ELISA. Il convient pour la détection de ISCU dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour ISCU anticorps (ABIN7246487)

Antigène: ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISCU est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ISCU anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human ISCU

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ISCU

Antigène: ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

Autre désignation: ISCU

Sujet: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 18 kDa

UniProt: Q9H1K1