ISCU anticorps (C-Term)
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- Antigène Voir toutes ISCU Anticorps
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
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Épitope
- AA 138-167, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ISCU est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
- Clone
- RB35591
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ISCU Anticorps primaire
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- Indications d'application
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).
: "MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2." dans: Cell metabolism, Vol. 10, Issue 4, pp. 273-84, (2009) (PubMed).
: "Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy." dans: Brain : a journal of neurology, Vol. 132, Issue Pt 8, pp. 2170-9, (2009) (PubMed).
: "Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein." dans: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 13, Issue 5, pp. 825-36, (2008) (PubMed).
: "Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance." dans: American journal of human genetics, Vol. 82, Issue 3, pp. 652-60, (2008) (PubMed).
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Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).
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- Antigène
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Autre désignation
- ISCU (ISCU Produits)
- Synonymes
- anticorps nifun, anticorps zC191D15.3, anticorps si:ch211-191d15.3, anticorps 2310020H20Rik, anticorps HML, anticorps ISU2, anticorps NIFU, anticorps NIFUN, anticorps hnifU, anticorps RGD1309562, anticorps AA407971, anticorps Nifu, anticorps Nifun, anticorps iron-sulfur cluster assembly enzyme ISCU, mitochondrial, anticorps iron-sulfur cluster assembly enzyme, anticorps iron-sulfur cluster assembly enzyme a, anticorps LOC409130, anticorps ISCU, anticorps iscua, anticorps Iscu
- Sujet
- Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
- Poids moléculaire
- 17999
- NCBI Accession
- NP_055116, NP_998760
- UniProt
- Q9H1K1
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