PTH1R
Reactivité: Humain, Boeuf (Vache), Porc, Chien
WB, IHC, IF, IC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:50-1:300, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
1.14 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
PTH1R
(Parathyroid Hormone 1 Receptor (PTH1R))
Autre désignation
PTH1R
Sujet
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]