LDLR anticorps

N° du produit ABIN7249770

Détail du produit anti-LDLR anticorps

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDLR est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to LDL Receptor

Isotype: IgG

Information d'application

Indications d'application: IHC 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LDLR

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Autre désignation: LDLR (LDLR Produits)

Synonymes: anticorps FH, anticorps FHC, anticorps LDLCQ2, anticorps Hlb301, anticorps LDLRA, anticorps LDLA, anticorps LDL receptor-2, anticorps fhc, anticorps ldlcq2, anticorps ldlr, anticorps ldlr2-a, anticorps LDL receptor 1, anticorps ldlr-a, anticorps ldlr-b, anticorps low density lipoprotein receptor, anticorps low density lipoprotein receptor a, anticorps low density lipoprotein receptor S homeolog, anticorps low density lipoprotein receptor L homeolog, anticorps LDLR, anticorps Ldlr, anticorps ldlra, anticorps ldlr.S, anticorps ldlr.L

Sujet: LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

UniProt: P01130, P35951, P35952

Pathways: Hepatitis C, Lipid Metabolism