XRCC4 anticorps

N° du produit ABIN7250143

L’anticorps Souris Monoclonal anti-XRCC4 a été validé pour WB, IF, IP et IHC (p). Il convient pour détecter XRCC4 dans des échantillons de Humain.

Aperçu rapide pour XRCC4 anticorps (ABIN7250143)

Antigène: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRCC4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8K2

Détail du produit anti-XRCC4 anticorps

Attributs du produit: Monoclonal Antibody

Purification: Protein A purification

Immunogène: Synthetic Peptide

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur XRCC4

Antigène: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Autre désignation: XRCC4

Sujet: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Poids moléculaire:

Observed_MW: 38 kDa

Calculated_MW: 38 kDa

UniProt: Q13426

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response