Filamin A anticorps (pSer2152)

N° du produit ABIN7250800

L’anticorps Lapin Polyclonal anti-Filamin A a été validé pour WB, ELISA et IHC (p). Il convient pour détecter Filamin A dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour Filamin A anticorps (pSer2152) (ABIN7250800)

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Filamin A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Filamin A anticorps

Épitope: pSer2152

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: FLNA

Sujet: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 280 kDa

Calculated_MW: 281 kDa

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location