CXCR4 anticorps (pSer339)

N° du produit ABIN7250818

L’anticorps Lapin Polyclonal anti-CXCR4 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter CXCR4 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour CXCR4 anticorps (pSer339) (ABIN7250818)

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CXCR4 anticorps

Épitope: pSer339

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4

Sujet: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire:

Observed_MW: 38 kDa

Calculated_MW: 40 kDa

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events