Caspase 1 anticorps (Cleaved-Asp210)

N° du produit ABIN7251010

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Caspase 1 anticorps (Cleaved-Asp210) (ABIN7251010)

Antigène: Caspase 1 (CASP1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caspase 1 anticorps

Épitope: Cleaved-Asp210

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human Caspase-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Caspase 1

Antigène: Caspase 1 (CASP1)

Autre désignation: CASP1

Sujet: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Poids moléculaire:

Observed_MW: 25 kDa

Calculated_MW: 45 kDa

UniProt: P29466

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome