MMP2 anticorps
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- Antigène Voir toutes MMP2 Anticorps
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Reactivité
- Humain, Rat, Souris, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MMP2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Synthesized peptide derived from the C-terminal region of human MMP-2
- Isotype
- IgG
- Top Product
- Discover our top product MMP2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Autre désignation
- MMP2 (MMP2 Produits)
- Synonymes
- anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793
- Sujet
- Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
- Poids moléculaire
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Observed_MW: 74 kDa
Calculated_MW: 74 kDa
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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