KLRC1 anticorps

N° du produit ABIN7256038

Détail du produit anti-KLRC1 anticorps

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLRC1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human KLRC1 (NP_015567.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KLRC1

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Autre désignation: KLRC1 (KLRC1 Produits)

Synonymes: anticorps rNKG2A, anticorps NKG2-A, anticorps NKG2A, anticorps KLRC1, anticorps CD159A, anticorps NKG2, anticorps CD159a, anticorps NKG2B, anticorps killer cell lectin like receptor C1, anticorps NKG2-A/NKG2-B type II integral membrane protein-like, anticorps killer cell lectin-like receptor subfamily C, member 3, anticorps killer cell lectin-like receptor subfamily C, member 1, anticorps Klrc1, anticorps KLRC1, anticorps NKG2A, anticorps KLRC3

Sujet: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Poids moléculaire:

Observed_MW: 26 kDa

Calculated_MW: 24 kDa/26 kDa

ID gène: 3821

UniProt: P26715