KLRC1 anticorps (N-Term)

N° du produit ABIN2856611

Détail du produit anti-KLRC1 anticorps

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLRC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Macaque rhésus, Chimpanzé

Réactivité croisée (Details): Rhesus Monkey (100 %), Chimpanzee (100 %)

Attributs du produit: Rabbit Polyclonal antibody to KLRC1 (killer cell lectin-like receptor subfamily C, member 1)
KLRC1 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: A431 , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.54 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur KLRC1

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Autre désignation: KLRC1 (KLRC1 Produits)

Synonymes: anticorps rNKG2A, anticorps NKG2-A, anticorps NKG2A, anticorps KLRC1, anticorps CD159A, anticorps NKG2, anticorps CD159a, anticorps NKG2B, anticorps killer cell lectin like receptor C1, anticorps NKG2-A/NKG2-B type II integral membrane protein-like, anticorps killer cell lectin-like receptor subfamily C, member 3, anticorps killer cell lectin-like receptor subfamily C, member 1, anticorps Klrc1, anticorps KLRC1, anticorps NKG2A, anticorps KLRC3

Sujet: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Cellular Localization: Membrane, Single-pass type II membrane protein

Poids moléculaire: 26 kDa

ID gène: 3821