This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.
anticorps rNKG2A, anticorps NKG2-A, anticorps NKG2A, anticorps KLRC1, anticorps CD159A, anticorps NKG2, anticorps CD159a, anticorps NKG2B, anticorps killer cell lectin like receptor C1, anticorps NKG2-A/NKG2-B type II integral membrane protein-like, anticorps killer cell lectin-like receptor subfamily C, member 3, anticorps killer cell lectin-like receptor subfamily C, member 1, anticorps Klrc1, anticorps KLRC1, anticorps NKG2A, anticorps KLRC3
Sujet
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.