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SNAP23 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement SNAP23 dans IHC. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN7257463

Aperçu rapide pour SNAP23 anticorps (ABIN7257463)

Antigène

Voir toutes SNAP23 Anticorps
SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Reactivité

  • 71
  • 18
  • 16
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 66
  • 4
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 62
  • 12
Polyclonal

Conjugué

  • 37
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SNAP23 est non-conjugé

Application

  • 40
  • 27
  • 25
  • 13
  • 13
  • 12
  • 10
  • 10
  • 7
  • 5
  • 5
  • 1
Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human SNAP23 (NP_003816.2).

    Isotype

    IgG
  • Indications d'application

    IHC 1:100-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

    Autre désignation

    SNAP23

    Sujet

    Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

    ID gène

    8773

    UniProt

    O00161
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