KIFAP3 anticorps

N° du produit ABIN7261082

Cet anticorps anti-KIFAP3 est un anticorps Lapin Polyclonal détectant KIFAP3 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour KIFAP3 anticorps (ABIN7261082)

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIFAP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIFAP3 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human KIFAP3 (NP_055785.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIFAP3

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Autre désignation: KIFAP3

Sujet: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 110 kDa

Calculated_MW: 82 kDa/86 kDa/91 kDa

ID gène: 22920

UniProt: Q92845

Pathways: Signalisation Hedgehog, Sensory Perception of Sound