BAF53A anticorps

N° du produit ABIN7261339

L’anticorps Lapin Polyclonal anti-BAF53A a été validé pour WB. Il convient pour détecter BAF53A dans des échantillons de Humain et Souris.

Aperçu rapide pour BAF53A anticorps (ABIN7261339)

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAF53A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAF53A anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ACTL6A (NP_004292.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BAF53A

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Autre désignation: ACTL6A

Sujet: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Poids moléculaire:

Observed_MW: 48 kDa

Calculated_MW: 43 kDa/47 kDa

ID gène: 86

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism