C4BPB anticorps

N° du produit ABIN7011062

Cet anticorps anti-C4BPB est un anticorps Lapin Polyclonal détectant C4BPB dans IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour C4BPB anticorps (ABIN7011062)

Antigène: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4BPB est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-C4BPB anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human C4BPB (NP_001017364.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C4BPB

Antigène: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Autre désignation: C4BPB

Sujet: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

ID gène: 725

UniProt: P20851

Pathways: Système du Complément