GLUD1 anticorps

N° du produit ABIN7263621

Cet anticorps Lapin Polyclonal détecte spécifiquement GLUD1 dans IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GLUD1 anticorps (ABIN7263621)

Antigène: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUD1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GLUD1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GLUD1 (NP_005262.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GLUD1

Antigène: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Autre désignation: GLUD1

Sujet: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

ID gène: 2746

UniProt: P00367

Pathways: Positive Regulation of Peptide Hormone Secretion, L'effet Warburg