MAX anticorps (pSer11)
Aperçu rapide pour MAX anticorps (pSer11) (ABIN7265060)
Antigène
Voir toutes MAX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pSer11
-
Attributs du produit
- Phosphorylated antibody
-
Purification
- Affinity purification
-
Immunogène
- A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- IF 1:50-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MAX (MYC Associated Factor X (MAX))
-
Autre désignation
- MAX
-
Sujet
- The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
-
ID gène
- 4149
-
UniProt
- P61244
-
Pathways
- Mitotic G1-G1/S Phases
Antigène
-