STOML2 anticorps (Intracellular)

N° du produit ABIN7043779

Cet anticorps Lapin Polyclonal détecte spécifiquement STOML2 dans WB. Il présente une réactivité envers Rat.

Aperçu rapide pour STOML2 anticorps (Intracellular) (ABIN7043779)

Antigène: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STOML2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STOML2 anticorps

Épitope: AA 208-222, Intracellular

Fonction: A Rabbit Polyclonal Antibody to Stomatin-like Protein 2

Specificité: Intracellular

Réactivité croisée: Humain, Souris, Rat

Homologie: Mouse,human - identical

Attributs du produit: Anti-STOML2/ Antibody (ABIN7043779, ABIN7044518 and ABIN7044519) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Stomatin-like protein 2 from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)EGTRESAINVAEGKK, corresponding to amino acid residues 208-222 of rat Stomatin-like protein 2

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:400-1:800

Commentaires:

Negative Control: (ABIN7237288)

Blocking Peptide: (ABIN7237288)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur STOML2

Antigène: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Autre désignation: STOML2

Sujet: Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2,Stomatin-like protein 2 (STOML2, SLP-2) is a key protein on the mitochondrial inner membrane and a member of the stomatin superfamily. STOML2 is widely expressed in human tissues such as the brain, lung, and kidneys and interacts with prohibitin-1 and 2. It plays an important role in numerous physiological processes including organizing sphingolipid and cholesterol-rich lipid rafts, regulating ion channel conductance, and linking other integral membrane proteins to the peripheral cytoskeleton1,2.STOML2 shares a consensus stomatin signature sequence that defines the stomatin gene family. However, it lacks a NH2-terminal hydrophobic domain shared by other members3.Studies show that STOML2 expression is upregulated in various human cancer tissues including gastric cancer, endometrial adenocarcinoma, and breast cancer. The protein may play an important role in the incidence and development of tumor and it is suggested that SLP-2 is a potential oncogene. Knockdown of STOML2 protein significantly restrains the viability, migration, and invasion of hepatoma cell line1,2.

Alternative names: STOML2/SLP-2, Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2

ID gène: 298203

NCBI Accession: NM_013442

UniProt: Q4FZT0

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2