SNCG anticorps (C-Term)

N° du produit ABIN7887059

Cet anticorps anti-SNCG Polyclonal Lapin (ABIN7887059) détecte spécifiquement SNCG dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour SNCG anticorps (C-Term) (ABIN7887059)

Antigène: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SNCG anticorps

Épitope: AA 96-108, C-Term

Fonction: A Rabbit Polyclonal Antibody to Gamma-Synuclein

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Not recommended for use with human samples.

Homologie: Mouse - identical

Attributs du produit: Anti-Gamma-Synuclein Antibody (ABIN7043802, ABIN7045184 and ABIN7045185) is a highly specific antibody directed against an epitope of the rat protein. It can be used in western blot analysis. It has been designed to recognize γ-Synuclein from mouse and rat samples. The antibody will not recognize the protein from human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)RKEDLEPPAQDQE, corresponding to amino acid residues 96 - 108 of rat gamma-Synuclein

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:200

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7237365)

Blocking Peptide: (ABIN7237365)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur SNCG

Antigène: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Autre désignation: SNCG

Sujet:

Synonyms: γ-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG

Description: γ-synuclein is a 127 amino acids protein that belongs to the synuclein family of proteins. Synucleins are natively unfolded proteins, i.e. they have no secondary or tertiary structure in solution and hence these proteins are heat stable. The unusual biophysical properties of synucleins are rooted in their characteristic primary sequence that includes a highly conserved N-terminal domain with an 11- residue repeat and a less conserved acidic C-terminal domain that contains many proline residues1.Mammalian γ-synuclein, encoded by BCSG1 (breast cancer specific gene 1), was discovered in a screen for breast cancer markers2. It is expressed in the peripheral nervous system in primary sensory neurons, sympathetic neurons, and motor neurons. It is also detected in the brain3, olfactory epithelium and breast/ovarian tumors4. Indeed, exogenous expression of this protein increases the invasive and metastatic potential of breast tumors5.The roles of synucleins are not fully elucidated but this group of conserved and unusual proteins contributes to diverse disease processes spanning neurodegenerative disease and cancer and hence, studying the synucleins specific cellular activity is very tempting and promising.

ID gène: 64347

NCBI Accession: NM_001330120

UniProt: O76070