Recombinant ErbB2/Her2 anticorps

N° du produit ABIN7072299

Cet anticorps anti-ErbB2/Her2 est un anticorps Souris Monoclonal détectant ErbB2/Her2 dans ELISA. Adapté pour Humain.

Aperçu rapide pour Recombinant ErbB2/Her2 anticorps (ABIN7072299)

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ErbB2/Her2 est non-conjugé

Application: ELISA

Clone: SER4

Détail du produit anti-ErbB2/Her2 anticorps

Fonction: Anti-HER2/neu [SER4], Mouse IgG1, kappa

Specificité: The antibody binds specifically to the extracellular domain of human ErbB-2.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: Recombinant HER2/neu.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The antibody binds to human ErbB-2, a receptor tyrosine kinase (RTK) controlling cell growth and microtubule stabilization. Full-length antibody or Fab fragments cross-linked by secondary antibody had a growth-inhibiting effect onf ErbB-2 positive MDA-MB-453 cells. This effect was not seen with Fab fragments alone.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur ErbB2/Her2

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Autre désignation: HER2/neu

Sujet: ERBB2, Receptor tyrosine-protein kinase erbB-2, human epidermal growth factor receptor 2,

UniProt: P04626

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development