Recombinant TGFA anticorps (N-Term)

N° du produit ABIN7072346

L’anticorps anti-TGFA Chimeric Lapin est utilisé pour la détection de TGFA dans des échantillons de Humain. Il a été validé pour ELISA, DB, ITC et XRC.

Aperçu rapide pour Recombinant TGFA anticorps (N-Term) (ABIN7072346)

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp TGFA est non-conjugé

Application: ELISA, Dot Blot (DB), Isothermal Titration Calorimetry (ITC), X-Ray Crystallography (XRC)

Clone: TAb2

Détail du produit anti-TGFA anticorps

Épitope: N-Term

Fonction: Anti-TGFalpha [tAb2], Rabbit IgG, kappa

Specificité:

tAb2 binds the N-terminal sequence of transforming growth factor alpha, VVSHFND (with residues 4 to 7 being the minimal binding epitope).

Application Notes original Clone: Human transforming growth factora (TGFa) consists of 50 amino acid residues with three disulphide bridges. It belongs to the family of epidermal growth factor related peptides and binds to EGFreceptor. It is involved in cell proliferation in healthy cells and is found in various cancer cells. Transfection of Fibroblasts with the TGFa gene induces tumor formation.

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: Biologically active hemocyanin-coupled human TGFalpha.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGFalpha

Sujet: TGFA, Transforming growth factor A

UniProt: P01135

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway