Recombinant DARC anticorps (N-Term)

N° du produit ABIN7072436

L’anticorps anti-DARC Monoclonal Souris est utilisé pour la détection de DARC dans des échantillons de Humain. Il a été validé pour WB, ELISA, FACS, BP et Inh.

Aperçu rapide pour Recombinant DARC anticorps (N-Term) (ABIN7072436)

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DARC est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Blocking Peptide (BP), Inhibition (Inh)

Clone: 2C3

Détail du produit anti-DARC anticorps

Épitope: N-Term

Fonction: Anti-DARC [2C3], Mouse IgG1, kappa

Specificité:

The antibody specifically binds to the pentapeptide FEDVW of the Duffy Antigen Receptor for Chemokines (DARC). The epitope is located on the N-terminal region on the RBC surface membrane. DARC is a glycoprotein chemokine receptor and the only known receptor for Plasmodium vivax.

Application Notes original Clone: The original antibody (mouse IgG1) was generated and used successfully in ELISA, FC, and inhibition assays, blocking DARC and IL-8 binding. The antibody's epitope was also characterized (Wasniowska et al., 2002, PMID: 12164140). This antibody was successfully used in a WB (Czerwinski et al., 2007 (PMID: 17382291), Smolarek et al., 2015 (PMID: 25706384)). This antibody was successfully used to inhibit P. Vivax invasion (Russell et al., 2011 (PMID: 21768300), Urusova et al., 2019 (PMID: 31133752)).

Purification: Protein A affinity purified

Immunogène: CHO cells transfected with cDNA encoding the Duffy glycoprotein.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur DARC

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Autre désignation: DARC

Sujet: Fy6, Duffy Antigen Receptor for Chemokines, NaM185-2C3

UniProt: Q4VBN9