Recombinant CSF1R anticorps

N° du produit ABIN7072608

Cet anticorps anti-CSF1R est un anticorps Lapin Chimeric détectant CSF1R dans WB, IHC, FACS et BP. Adapté pour Souris.

Aperçu rapide pour Recombinant CSF1R anticorps (ABIN7072608)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Peptide (BP)

Clone: AFS98

Détail du produit anti-CSF1R anticorps

Fonction: Anti-CD115/M-CSFR [AFS98], Rabbit IgG, kappa

Specificité: This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: This antibody was raised against CD115.

Isotype: IgG kappa

Information d'application

Indications d'application: AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4 % paraformaldehyde-fixed and decalcified bones (Dong et al., 2016).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CD115/M-CSFR

Sujet: CSF-1R, Macrophage colony-stimulating factor 1 receptor, Csf1r, CD115, CSF-1 receptor, EC 2.7.10.1, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms

UniProt: P09581

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization