Recombinant C5AR1 anticorps (AA 1-31)

N° du produit ABIN7072651

Cet anticorps Lapin Chimeric détecte spécifiquement C5AR1 dans WB, FACS, ELISA, IP, Func et BP. Il présente une réactivité envers Humain, Boeuf (Vache), Lapin et Furet.

Aperçu rapide pour Recombinant C5AR1 anticorps (AA 1-31) (ABIN7072651)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Boeuf (Vache), Lapin, Furet

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp C5AR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func), Blocking Peptide (BP)

Clone: S5-1

Détail du produit anti-C5AR1 anticorps

Épitope: AA 1-31

Fonction: Anti-C5aR [S5/1], Rabbit IgG, kappa

Specificité: S5/1 antibody recognizes the C5aR (CD88) protein, a 43 kDa receptor of C5a component of the complement cascade.

Réactivité croisée: Boeuf (Vache), Furet, Lapin

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunizing mice with a synthetic peptide corresponding to C5a-R, amino acids: 1-31 (N terminal).

Isotype: IgG kappa

Information d'application

Indications d'application: S5/1 antibody inhibits C5a binding to its receptor C5aR (Oppermann et al., 1993). Furthermore, this antibody has been widely applied in the detection and analysis of C5aR via various methods. For instance, it was used in a flow cytometric study on peripheral blood lymphocytes where it was shown to bind to monocytes and granulocytes (Oppermann et al., 1993). It was also utilized in the Western blot experiments comparing C5aR expression in different groups of mice (Panayiotou et al., 2017). S5/1 was also successfull in labelling C5aR in the paraffin-embedded immunohistochemical samples of umbilical arteries (Fortin et al., 2002).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: C5aR

Sujet: CD88, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR

UniProt: P21730

Pathways: Système du Complément