Caspase 3 anticorps (cleaved)

N° du produit ABIN7073336

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 3 dans IHC et IF. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 5+ publications.

Aperçu rapide pour Caspase 3 anticorps (cleaved) (ABIN7073336)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Caspase 3 anticorps

Épitope: cleaved

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse caspase3

Information d'application

Indications d'application: IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Caspase 3 (ABIN7073336)

Chen, Jin, Wang, Liu, Luo, Tian, Cai, Meng, Bi, Wang, Xie, Yu, Li, Dong, Cai, Jia, Wei, Jia: "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling." dans: JCI insight, Vol. 5, Issue 3, (2021) (PubMed).

Chang, Shang, Yuan, Guo, Wang: "EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation." dans: Cancer cell international, Vol. 21, Issue 1, pp. 531, (2021) (PubMed).

Wang, Zheng, Che, Han, Li, Wang, Liu, Shi, Sun: "Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway." dans: Experimental and therapeutic medicine, Vol. 22, Issue 6, pp. 1400, (2021) (PubMed).

Elhadidy, Elmasry, Elsayed, El-Nablaway, Hamed, Elalfy, Rabei: "Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats." dans: Heliyon, Vol. 7, Issue 10, pp. e08171, (2021) (PubMed).

Ma, Xu, Huang, Gao, Zhou, Li, Zhang: "Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation." dans: Frontiers in physiology, Vol. 12, pp. 706359, (2021) (PubMed).

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: Caspase-3

Sujet: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).

ID gène: 12367

NCBI Accession: NP_001271338

UniProt: P70677

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation