CD3 anticorps

N° du produit ABIN7073386

Cet anticorps anti-CD3 est un anticorps Lapin Polyclonal détectant CD3 dans IHC, IF et WB. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour CD3 anticorps (ABIN7073386)

Antigène: CD3

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)

Détail du produit anti-CD3 anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse CD3

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:250-1:1000/1:250-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-CD3 (ABIN7073386)

Feng, Yang, Luo, Sun, Lv, Wan, Guan, Xiao, Liu, Li, Dong, Yang: "The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." dans: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).

He, Wang, Lu, Yang, Xue, Zhu, Zhang, Fan: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." dans: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).

Chen, Gu, Jia, Liu, Liu, Liu, Xu, Lin, Lin, Liu, Chen, Xu, Yuan, Zhang, Zhang, Xiao, Gu: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." dans: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.

Poids moléculaire: 21 kDa

ID gène: 12501

NCBI Accession: NP_031674

UniProt: P22646

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway