MYLK3 anticorps

N° du produit ABIN7074736

Cet anticorps anti-MYLK3 Polyclonal Lapin (ABIN7074736) détecte spécifiquement MYLK3 dans IHC et IF. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour MYLK3 anticorps (ABIN7074736)

Antigène: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MYLK3 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse MYLK3/MLCK

Information d'application

Indications d'application: IHC/IF (M,R) 1:600-1:1200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MYLK3

Antigène: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Autre désignation: MYLK3/MLCK

Sujet: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

ID gène: 213435

NCBI Accession: NP_001284541

UniProt: Q3UIZ8

Pathways: Regulation of Muscle Cell Differentiation