RAP1 anticorps
Aperçu rapide pour RAP1 anticorps (ABIN7075857)
Antigène
Voir toutes RAP1 (TERF2IP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse RAP1
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Indications d'application
- WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000/1:500-1:3000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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Autre désignation
- RAP1
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Sujet
- Telomeric repeat-binding factor 2-interacting protein 1 acts both as a regulator of telomere function and as a transcription regulator. it is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
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Poids moléculaire
- 46 kDa
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ID gène
- 57321
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UniProt
- Q91VL8
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Pathways
- Cycle Cellulaire, Telomere Maintenance
Antigène
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