CD21 anticorps (FITC)

N° du produit ABIN7076447

Cet anticorps anti-CD21 Monoclonal Souris conjugué à FITC (Clone HB5) (ABIN7076447) détecte spécifiquement CD21 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD21 anticorps (FITC) (ABIN7076447)

Antigène: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD21 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade (Analyte)

Clone: HB5

Détail du produit anti-CD21 anticorps (FITC)

Fonction: CD21 FITC Antibody

Attributs du produit: The mouse monoclonal antibody produced by clone HB5 binds to complement receptor 2 (CR2), known as CD21, a 145 kDa glycoprotein of the complement control protein family. It is a receptor for the complement components C3d and C3g and, under pathological circumstances, for the Epstein-Barr virus (EBV). As complement breakdown fragments remain bound to the agent initiating the complement activation in the first place, CD21 plays an important role in the uptake of immunocomplexes. In addition, it plays a role in B cell development and activation as well as memory B cell survival. Thus, it is a key component in developing and maintaining humoral immune response to T-dependent antigens. CD21 associates with CD19, CD81 and the B cell receptor. The cell surface marker CD21 is expressed on mature B cells and follicular dendritic cells. It is used as a cell marker for the phenotyping of leukemias.

Purification: Purified

Pureté: >95 %

Immunogène: Human complement receptor 2 (CR2)

Isotype: IgG2a

Information d'application

Indications d'application: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur CD21

Antigène: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Autre désignation: CD21

ID gène: 1380

UniProt: P20023

Pathways: Système du Complément