ITGAL anticorps (PE)
Aperçu rapide pour ITGAL anticorps (PE) (ABIN7076858)
Antigène
Voir toutes ITGAL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD11a PE Antibody
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Attributs du produit
- The clone TS1/22 recognizes a 170-180 kDa alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but is not expressed by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce the immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and may be a reason for in vivo tumor generation.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Human HLA-DRCTL line cytolytic T-lymphocytes
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- ITGAL (Integrin alpha-L (ITGAL))
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Autre désignation
- CD11a
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ID gène
- 3683
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UniProt
- P20701
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Antigène
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