CD73 anticorps (FITC)
Aperçu rapide pour CD73 anticorps (FITC) (ABIN7077428)
Antigène
Voir toutes CD73 (NT5E) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD73 FITC Antibody
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Attributs du produit
- The clone AD2, a mouse monoclonal antibody recognizes a 70kD glycophosphatidylinositol (GPI)-linked 5'nucleotidase (or 5'-Ecto-nucleotidase) cell surface antigen known as CD73. It is widely expressed on various immune as well as non-immune cells including T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, epithelial cells, etc. CD73 catalyzes the conversion of extracellular nucleosides to adenosine and modulates immune responses. Administration of CD73 inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Pre-B leukemia cell line
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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Autre désignation
- CD73
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ID gène
- 4907
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UniProt
- P21589
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Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
Antigène
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