Cet anticorps anti-MHC Class II HLA-DP/DQ/DR Monoclonal Souris conjugué à Biotin (Clone IVA12) (ABIN7077536) détecte spécifiquement MHC Class II HLA-DP/DQ/DR dans FACS.
L’anticorps est réactif avec des échantillons de Humain.
Aperçu rapide pour MHC Class II HLA-DP/DQ/DR anticorps (Biotin) (ABIN7077536)
Antigène
MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
Reactivité
Humain
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp MHC Class II HLA-DP/DQ/DR est conjugé à/à la Biotin
Application
Flow Cytometry (FACS)
Classe de qualité
GMP Grade
Clone
IVA12
Fonction
Anti-HLA-DR, DP, DQ Biotin Antibody
Attributs du produit
The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.