ABCA1 anticorps

N° du produit ABIN7090762

L’anticorps Souris Monoclonal anti-ABCA1 a été validé pour WB, ICC et IF. Il convient pour détecter ABCA1 dans des échantillons de Souris.

Aperçu rapide pour ABCA1 anticorps (ABIN7090762)

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABCA1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: H5D5

Détail du produit anti-ABCA1 anticorps

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein G.

Immunogène: KLH conjugated synthetic peptide derived from human ABCA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF()
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ABCA1

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Autre désignation: ABCA1

Sujet:

Synonyms: ABC1, ATP binding cassette transporter A1, ABC 1, ABC Transporter 1, ABCA 1, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding Cassette Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD, ABCA1_HUMAN.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]

ID gène: 19

UniProt: O95477

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism